The 11th Annual Dublin Cystinosis Workshop will be held on 24th and 25th April 2025. There will be a cross-over scientific and family agenda on 25th April and a family only event on 26th April.
Cystinosis Ireland is proud to announce that the 11th Annual Dublin Cystinosis Workshop 2025 will be held in person on Thursday and Friday, 24th and 25th April 2025 (Saturday 26th is the family only agenda), at The Royal Marine Hotel, Dun Laoghaire, Co. Dublin, Ireland.
This year, the Cystinosis Ireland Research Committee and the DCW Scientific Committee have decided to have a workshop which will be focused on “Kidney aspects of cystinosis - emphasising research development”.
The Dublin Cystinosis Workshop is the only annual scientific workshop in Europe focused on cystinosis. Its aim is to share new research developments in the area of cystinosis and to stimulate discussions and collaborations, converting new ideas into research that moves the field forward.
This is a closed workshop, and participation is only possible by invitation, or invitation following abstract selection.
Cystinosis Ireland is proud to announce that the 11th Annual Dublin Cystinosis Workshop 2025 will be held in person on Thursday and Friday, 24th and 25th April 2025 (Saturday 26th is the family only agenda), at The Royal Marine Hotel, Dun Laoghaire, Co. Dublin, Ireland.
This year, the Cystinosis Ireland Research Committee and the DCW Scientific Committee have decided to have a workshop which will be focused on “Kidney aspects of cystinosis - emphasising research development”.
This is a closed workshop, and participation is only possible by invitation, or invitation following abstract selection. Early-stage postdoctoral researchers and PhD candidates are invited to submit abstracts on any aspect of cystinosis research for inclusion at the scientific poster session of the 11th Annual Dublin Cystinosis Workshop.
Even though the theme of the workshop is Kidney aspects of cystinosis we welcome abstracts on any aspect of cystinosis research.
Please see here the details for abstract submission. Deadline for submission of abstracts is 5pm (Irish time) 15th January 2025.
Abstracts will be peer reviewed and based on this review you may be invited to attend the DCW 2025 for the poster presentation.
The meeting will take place over two days 24 & 25 April
Day 1 Thursday 24th April 2025
SESSION ONE – Theme: Newborn screening
Chair: Bert van den Heuvel
| Start | Speaker | Topic | Institution | Country |
|---|---|---|---|---|
| 11.45 | Koenraad Veys and Anne Marie O’Dowd | Introduction | Cystinosis Ireland | Ireland and Belgium |
| 12.00 | Avril Daly | Newborn Screening, a EURORDIS perspective | EURORDIS | Ireland |
| 12:30 | Marcel Neelen | NGS-based approaches for Newborn Screening: a Dutch perspective | NGS-based approaches for Newborn Screening: a Dutch perspective | NGS-based approaches for Newborn Screening: a Dutch perspective |
SESSION TWO - Theme: Prevention (of progression) of cystinosis kidney disease: novel approaches
Chair: Jennifer Hollywood
| Start | Speaker | Topic | Institution | Country |
|---|---|---|---|---|
| 14.00 | Elena Levtchenko | mRNA-based therapy in cystinosis | mRNA-based therapy in cystinosis | Netherlands |
| 14.30 | Paul Goodyer | Kidney-targeted Lipid Nanoparticle-based mRNA therapy | Mc Gill University | Canada |
| 15.00 | Giusi Prencipe | NLRP2 inflammasome and inflammation in cystinosis kidney disease | Bambino Gesu | Italy |
| 15.45 | Jennifer Hollywood | mTOR inhibition as a therapeutic approach in cystinosis | University of Auckland/ University of Cork | New Zealand/ Ireland |
| 16.15 | Ester De Leo | Effect of Luteolin on chronic kidney disease in cystinosis | Bambino Gesu | Italy |
| 16.45 | Francesco Bellomo | Ketogenic diet and progression of kidney disease in cystinosis animal models | Bambino Gesu | Italy |
SESSION THREE: KEYNOTE – The Ketogenic Diet in prevention and treatment of disease
Chair: Elena Levtchenko
| Start | Speaker | Topic | Institution | Country |
|---|---|---|---|---|
| 17.30 | Simon Heales | Understanding the ketogenic diet in prevention and treatment of disease | UCL, GOSH, London | United Kingdom |
Theme: Funding opportunities
Chair: Achim Treumann
| Start | Speaker | Topic | Institution | Country |
|---|---|---|---|---|
| 18.00 | Martha Cahill | Update on the Future of Health Calls | Enterprise Ireland | Ireland |
| 19.00 | Close |
Day 2 Friday 25th April 2025
SESSION FOUR & KEYNOTE – Theme: Kidney metabolism in health & disease
Chair: Elena Levtchenko
| Start | Speaker | Topic | Institution | Country |
|---|---|---|---|---|
| 08.30 | Markus Rinschen | Kidney and renal proximal tubule metabolism in health and disease | Aarhus University | Denmark |
| 09.30 | Sante Princiero Berlingerio | Modulation of energy metabolism in cystinosis | Emma Children’s Hospital, Amsterdam | The Netherlands |
SESSION FIVE – Theme: Kidney regeneration, future kidney replacement therapy perspectives, and kidney disease modelling
Chair: Koenraad Veys
| Start | Speaker | Topic | Institution | Country |
|---|---|---|---|---|
| 10.20 | Bart Smeets | Regeneration of the proximal tubule compartment and potential therapeutic strategies | Radboud UMC Nijmegen | The Netherlands |
| 10.50 | Fanny Oliveira Arcolino | Employing the kidney regeneration toolbox for cell-based therapy and optimization of kidney grafts | Amsterdam UMC | The Netherlands |
| 11.20 | Moin Saleem | Gene therapeutic approaches to podocytopathies | University of Bristol | UK |
| 11.50 | Anne Metje van Genderen | Modelling the healthy and diseased kidney in vitro using organoids & 3D- printing | Utrecht University | The Netherlands |
SESSION SIX - Theme: Clinical perspectives in cystinosis
Chair: Francesco Emma
| Start | Speaker | Topic | Institution | Country |
|---|---|---|---|---|
| 13.30 | Herbie Newell | CF-10: an update | University of Sunderland | UK |
| 14.05 | Katharina Hohenfellner | Clinical guidelines in cystinosis | Roseheim | Germany |
| 14.40 | Angela Ferruli | The potential of desmopressin treatment in cystinosis. | Amsterdam UMC | The Netherlands |
SESSION SEVEN: Cystinosis Ireland funded Research Project: Updates
Chair: Anne Marie O'Dowd
| Start | Speaker | Topic | Institution | Country |
|---|---|---|---|---|
| 15.15 | Minnie Sarwal/Swastika Sur | UCSF, California | USA | |
| Rik Gijsbers | KU Leuven | Belgium | ||
| Joyce Senior | University College Dublin | Ireland | ||
| Anuj Chauhan - pre recorded | Colorado School of Mines | USA | ||
| 16.30 | Non scientific presentations for families | |||
| 17.00 | Mick Swift and Anne Marie O'Dowd | Wrap up | Cystinosis Ireland | Ireland |
| 17.10 | Poster session | |||
| 18.00 | Meeting close |
Our Speakers
The DCW draws some of the most well known experts in the clinical and research fields as well as new and aspiring members of our community. As speakers are confirmed, they will be updated here.
Organising Committee
Cystinosis Ireland is grateful for the skill, knowledge and expertise of our organising committee in developing this workshop.
Dr Koenraad Veys - MD PHD, Paediatrician, Consultant in Pediatric Nephrology in UZ Leuven - Scientific Chairperson
Prof Elena Levtchenko - UMC Amsterdam
Prof Francesco Emma - Bambino Gesù Children’s Hospital IRCCS
Prof Bert van der Heuvel - KU Leuven
Dr Jennifer Hollywood - UCC
Prof Atif Awan - Consultant Paediatric Nephrologists, Temple Street Children’s University Hospital, Dublin
Dr Ruth Davis - Cystinosis Ireland Research Committee Member
Dr Thomas J McDonald - Bristol Myers Squibb and Cystinosis Ireland Board Member
Ms Anne Marie O’Dowd - Chairperson, Cystinosis Network Europe and Cystinosis Ireland Board Member
Ms Eibhlis Shanahan - Cystinosis Ireland Research Committee Member
Dr Achim Treumann - Director, Analytical Formulation Sciences and Site Head at KBI Biopharma BV – Cystinosis Ireland Scientific Advisor
Dr Tracey McCauley - Cystinosis Ireland Research Manager
Ms Denise Dunne - Cystinosis Ireland Operations Manager